Extraskeletal Myxoid Chondrosarcoma

A rare malignant soft tissue neoplasm that originates from CHONDROBLASTS. It is most common in male middle-aged and elderly individuals and often presents as deep lesions in soft tissue of the extremities. Malignancy is low, but recurrence and METASTASIS can occur many years after the initial diagnosis. Histologically, the tumors consist of a mixture of cellular and myxoid stromal components. Can be caused by somatic chromosomal translocations resulting in fusions between the NR4A3 and EWSR1 genes, and NR4A3 and TAF15 genes. OMIM: 612237

Also Known As:

Chondrosarcoma, Extraskeletal Myxoid

Neoplasms: 1361496
- Neoplasms by Histologic Type: 2
  - Connective and Soft Tissue Neoplasms: 1
    - Sarcoma: 23591
      - Chondrosarcoma: 2511
        Extraskeletal Myxoid Chondrosarcoma: 72
    - Extraskeletal Myxoid Chondrosarcoma: 72
    - Connective Tissue Neoplasms: 9
      - Chondrosarcoma: 2511
        Extraskeletal Myxoid Chondrosarcoma: 72

H Sjögren Selected Research

H Sjögren Research Topics

Disease

Drug/Important Bio-Agent (IBA)